MicroRNA-320d regulates tumor growth and invasion by promoting FoxM1 and predicts poor outcome in gastric cardiac adenocarcinoma

Table 2 Correlation between miR-320d or FoxM1 expression with clinicopathological features in 60 GCA patients

Characteristics	No. of patients	Relative miR-320d expression	P	Relative FoxM1 expression	P
Age (years)
< 60	19	6.458 ± 0.272	0.106	7.151 ± 0.360	0.133
≥ 60	41	6.392 ± 0.146		6.924 ± 0.553
Male/female
Male	44	6.424 ± 0.201	0.225	7.115 ± 0.628	0.151
Female	16	6.405 ± 0.105		6.937 ± 0.563
The stomach diseases
No	18	6.438 ± 0.216	0.175	7.026 ± 0.660	0.207
Yes	42	6.398 ± 0.281		6.973 ± 0.478
Family history of cancer
No	27	6.419 ± 0.136	0.353	7.091 ± 0.512	0.116
Yes	33	6.409 ± 0.237		6.957 ± 0.730
Pathological grade
Low differentiated	19	6.607 ± 0.116	0.054	7.103 ± 0.621	0.051
Middle and high differentiated	41	6.492 ± 0.135		6.811 ± 0.672
Clinical stage
Low grades I–II	12	6.420 ± 0.127	0.307	7.020 ± 0.473	0.201
High grades III–IV	48	6.405 ± 0.138		6.977 ± 0.337
Lymph node metastasis
Negative	10	6.501 ± 0.217	0.057	6.863 ± 0.445	0.044
Positive	50	6.399 ± 0.138		7.162 ± 0.706

P value < 0.05 is marked in italic, which means there is a significant difference between the two groups
GCA Gastric cardia adenocarcinoma

ISSN: 2045-3701