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Fig. 2 | Cell & Bioscience

Fig. 2

From: MicroRNA-7: expression and function in brain physiological and pathological processes

Fig. 2

Schematic diagram of the regulatory mechanism of miR-7 expression. MiR-7 is transcribed from three different genomic loci on chromosomes 9, 15, 19 into primary miR-7 transcripts (pri-miR-7-1, pre-miR-7-2, pri-miR-7-3 respectively), which are processed into hairpin precursor molecules pre-miR-7, and then further into the same mature miR-7 sequences. There are always some molecules which affect miR-7 transcription involved in this process. Mature miR-7 sequence can target mRNAs to repress their expression, on the contrary, other antisense sequences interfere with miR-7 level

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