Table 1 The functional characterization of lncRNAs on neural related stem cells self-renewal
From: The functions of long non-coding RNAs in neural stem cell proliferation and differentiation
LncRNA name | Mechanism | Biological function | References |
|---|---|---|---|
Trincr1 | Restrain FGF/ERK signalling | Suppress NPCs self-renewal | |
LincRNA1230 | Interact with Wdr5 | Block ESCs transformation into NPCS | [31] |
Linc00115 | Activated by TGF-β, miR-200 s/ZEB1, miR200s/ZNF596/EZH2/STAT3 | Promote GSC self-renewal | [33] |
TUG1 | Activated by Notch, sponging of miR-145 and recruiting polycomb via YY1 | Promote GSC self-renewal | [34] |
Linc00152 | miR-103a-3p/FEZF1 axis | Promote GSC proliferation | [35] |
ZNF281 | NF-κB1 pathway | Inhibit GSC self-renewal | [36] |
TALNEC2 | Regulated by E2F1, miR-21/miR-191 | Promote GSC self-renewal | [37] |
Linc01198 | Enhancing the NEDD4-1-dependent inhibition of PTEN | Promote glioma proliferation | [38] |