Fig. 1

The voltage-gated Na⁺ channel and T-type Ca²⁺ channel expression of sensory neurons in different stages of HSV-1 infection. Most of the sensory neurons express abundant voltage-gated Na⁺ channels and T-type Ca²⁺ channels. HSV-1 lytic infection of sensory neurons induces a significant decrease of these channels, HSV-1 latency establishment decrease these channels, HSV-1 latency maintenance restore theses channels or even increase these channels