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Table 3 Integration of pathways of both the metabolites and metabolic genes

From: Integrated analysis of transcriptomic and metabolomic profiling reveal the p53 associated pathways underlying the response to ionizing radiation in HBE cells

Pathway name

Match status

P

Impact

Fructose and mannose metabolism

1/40

0.37213

0.25641

Tyrosine metabolism

3/88

0.077606

0.22989

Pyrimidine metabolism

2/99

0.31535

0.22449

Nitrogen metabolism

2/10

0.0054

0.22222

Glutathione metabolism

3/56

0.024996

0.21818

Glycolysis or Gluconeogenesis

3/61

0.03124

0.2

Phenylalanine metabolism

1/21

0.21603

0.2

Pyruvate metabolism

1/45

0.40794

0.18182

Arachidonic acid metabolism

5/81

0.001919

0.175

Propanoate metabolism

1/48

0.42847

0.17021

Purine metabolism

2/166

0.57811

0.1697

Thiamine metabolism

1/14

0.14958

0.15385

Biotin metabolism

1/21

0.21603

0.15

Taurine and hypotaurine metabolism

1/16

0.1691

0.13333

Retinol metabolism

1/47

0.42171

0.13043

Linoleic acid metabolism

1/17

0.17869

0.125

Drug metabolism-cytochrome P450

2/98

0.31104

0.1134

Ether lipid metabolism

1/39

0.36472

0.10526

Nicotinate and nicotinamide metabolism

2/42

0.082504

0.097561

Alpha-Linolenic acid metabolism

1/22

0.2251

0.095238

Glycine, serine and threonine metabolism

2/68

0.18248

0.089552

Primary bile acid biosynthesis

2/92

0.28513

0.087912

Pentose phosphate pathway

1/47

0.42171

0.086957

Glycerophospholipid metabolism

2/86

0.25918

0.070588

Histidine metabolism

1/32

0.31045

0.064516

Fatty acid degradation

2/102

0.32824

0.059406

Starch and sucrose metabolism

1/43

0.39386

0.047619

Fatty acid biosynthesis

1/129

0.78338

0.046875

beta-Alanine metabolism

1/44

0.40094

0.046512

Cysteine and methionine metabolism

1/71

0.56461

0.042857

Glyoxylate and dicarboxylate metabolism

1/56

0.47992

0.036364

Sphingolipid metabolism

1/58

0.49207

0.035088

Folate biosynthesis

1/61

0.50978

0.033333

Metabolism of xenobiotics by cytochrome P450

2/145

0.50302

0.027778

Steroid hormone biosynthesis

1/199

0.90892

0.020202