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Table 3 Integration of pathways of both the metabolites and metabolic genes

From: Integrated analysis of transcriptomic and metabolomic profiling reveal the p53 associated pathways underlying the response to ionizing radiation in HBE cells

Pathway nameMatch statusPImpact
Fructose and mannose metabolism1/400.372130.25641
Tyrosine metabolism3/880.0776060.22989
Pyrimidine metabolism2/990.315350.22449
Nitrogen metabolism2/100.00540.22222
Glutathione metabolism3/560.0249960.21818
Glycolysis or Gluconeogenesis3/610.031240.2
Phenylalanine metabolism1/210.216030.2
Pyruvate metabolism1/450.407940.18182
Arachidonic acid metabolism5/810.0019190.175
Propanoate metabolism1/480.428470.17021
Purine metabolism2/1660.578110.1697
Thiamine metabolism1/140.149580.15385
Biotin metabolism1/210.216030.15
Taurine and hypotaurine metabolism1/160.16910.13333
Retinol metabolism1/470.421710.13043
Linoleic acid metabolism1/170.178690.125
Drug metabolism-cytochrome P4502/980.311040.1134
Ether lipid metabolism1/390.364720.10526
Nicotinate and nicotinamide metabolism2/420.0825040.097561
Alpha-Linolenic acid metabolism1/220.22510.095238
Glycine, serine and threonine metabolism2/680.182480.089552
Primary bile acid biosynthesis2/920.285130.087912
Pentose phosphate pathway1/470.421710.086957
Glycerophospholipid metabolism2/860.259180.070588
Histidine metabolism1/320.310450.064516
Fatty acid degradation2/1020.328240.059406
Starch and sucrose metabolism1/430.393860.047619
Fatty acid biosynthesis1/1290.783380.046875
beta-Alanine metabolism1/440.400940.046512
Cysteine and methionine metabolism1/710.564610.042857
Glyoxylate and dicarboxylate metabolism1/560.479920.036364
Sphingolipid metabolism1/580.492070.035088
Folate biosynthesis1/610.509780.033333
Metabolism of xenobiotics by cytochrome P4502/1450.503020.027778
Steroid hormone biosynthesis1/1990.908920.020202