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Fig. 5 | Cell & Bioscience

Fig. 5

From: Nonalcoholic fatty liver disease experiences accumulation of hepatic liquid crystal associated with increasing lipophagy

Fig. 5

Birefringence recovery by liquid crystal hepatic lipid droplets after an isotropic lipid droplet transition. Images of HiF diet induced NAFLD HLD phase transition from liquid crystal to isotropic lipid droplet are shown in ah. The resumption of birefringence as HLD regain liquid crystalline form is shown in ip. Optical activity of this process is quantified in q, r and t. q Birefringence density of the initial liquid crystal, r the lack of birefringence in anisotropic hepatic lipid droplets, and s birefringence density of recovered liquid crystal HLDs. t, u Demonstrate that both the initial and recovered liquid crystalline HLDs exhibit signature Maltese cross birefringence. Scale bars are 40 μm in ap; 25 μm in t and u

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