OTUB1-mediated deubiquitination of FOXM1 up-regulates ECT-2 to promote tumor progression in renal cell carcinoma

Cell & Bioscience

Table 1 Association between OTUB1 expression and patients’ clinicopathological features

Variable	Total	OTUB1 expression		P value
Variable	Total	Low expression (< median)	High expression (≥ median)	P value
Number	67	33	34
Gender				0.365
Male	41	22	19
Female	26	11	15
Age (years)				0.393
< 57	33	18	15
≥ 57	34	15	19
T stage				0.007*
T_1–2	49	29	20
T_3–4	18	4	14
N stage				0.026*
N₀	51	29	22
N_1–2	16	4	12
M stage				0.019*
M₀	53	30	23
M₁	14	3	11
Histological grade				0.000*
G_1–2	42	28	14
G_3–4	25	5	20
TNM stage				0.006*
I–II	44	27	17
III–IV	23	6	17

ISSN: 2045-3701