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Fig. 3 | Cell & Bioscience

Fig. 3

From: OTUB1-mediated deubiquitination of FOXM1 up-regulates ECT-2 to promote tumor progression in renal cell carcinoma

Fig. 3

OTUB1 suppressed ubiquitination of FOXM1 in RCC. a The effect of OTUB1 knockdown on FOXM1 mRNA expression in Caki-1 and 786-O cells. b The effect of OTUB1 knockdown on FOXM1 protein expression in Caki-1 and 786-O cells. ** represents siOTUB1 vs. siNC, p < 0.01. c The effect of OTUB1 knockdown on FOXM1 ubiquitination in Caki-1 and 786-O cells. d The effect of OTUB1 knockdown on FOXM1 protein expression in Caki-1 and 786-O cells under CHX treatment. e The effect of OTUB1 knockdown on FOXM1 protein expression in Caki-1 and 786-O cells under MG132 treatment

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