Fig. 2

Knockdown of OTUB1 suppressed cell proliferation, migration and invasion of RCC. a Knockdown efficiency of siOTUB1 in Caki-1 and 786-O cells as measured by qRT-PCR. ** represents siOTUB1 vs. siNC, p < 0.01. b The effect of OTUB1 knockdown on cell viability of Caki-1 and 786-O cells. * represents siOTUB1 vs. siNC, p < 0.05. c The effect of OTUB1 knockdown on cell proliferation of Caki-1 and 786-O cells. * represents siOTUB1 vs. siNC, p < 0.05. d The effect of OTUB1 knockdown on cell migration of Caki-1 and 786-O cells. *, ** represents siOTUB1 vs. siNC, p < 0.05, p < 0.01. e The effect of OTUB1 knockdown on cell invasion of Caki-1 and 786-O cells. *, ** represents siOTUB1 vs. siNC, p < 0.05, p < 0.01