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Fig. 1 | Cell & Bioscience

Fig. 1

From: Botulinum toxin type A promotes microglial M2 polarization and suppresses chronic constriction injury-induced neuropathic pain through the P2X7 receptor

Fig. 1

BTX-A elevated pain threshold in NP rats. Sprague–Dawley rats were randomly divided into the four groups (n = 10/group): Sham, CCI-induced NP, BTX-A-10 (rats were administered 10 U/kg BTX-A following CCI), and BTX-A-20 group (rats were administered 20 U/kg BTX-A following CCI). The mechanical withdrawal threshold (MWT; a) and thermal withdrawal latency (TWL; b) was measured at 0, 3, 5, 7, 10, 12, 14 days after induction of CCI. **P < 0.01, vs. Sham; #P < 0.05, ##P < 0.01, vs. NP

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