Fig. 2
From: Fanconi anemia pathway as a prospective target for cancer intervention
Alterations in FA genes are common in cancers. a Among the surveyed 10,202 tumors (no tissue origin filter) in the database of TCGA over 65% carry FA gene alterations (Affected). b The patient frequency of FA and frequency of FA SSM-affected cancers (total 6653 FA affected cases) are superimposed to reveal a significantly different distribution across the 22 FA genes. c Stacked column presentation of the frequency of copy number loss, copy number gain and SSM among FA affected cancer cases. d Differential gene expression with p value under 0.05 and log2 (fold change) > 0.5 of every FA gene within a panel of 7 cancer types were plotted in a heatmap fashion