Circular RNA expression profile in blood according to ischemic stroke etiology

Cell & Bioscience

Table 2 Deregulated circRNA chosen for qPCR validation

Regulation	CircRNA	CircRNA type	FC (abs)	P-value	Chromosome position			Gene symbol
Up	hsa_circRNA_001359	intronic	7.0479384	0.002611197	chr1	169663839	169664181	SELL
Up	hsa_circRNA_103559	exonic	4.8769307	0.035206182	chr3	196118683	196120490	UBXN7
	hsa_circRNA_104220	exonic	4.8572966	0.026033314	chr6	150092297	150094305	PCMT1
Down	hsa_circRNA_102488	exonic	2.7229035	8.17917E−05	chr19	18684102	18684558	UBA52
Down	hsa_circRNA_104748	exonic	2.3292681	0.001448543	chr9	20907148	20929595	FOCAD

CircRNA deregulated circRNA with greater intensity values in atherotrombotic stroke patients compared with cardioembolic; circRNA_type: the circRNAs are classified into 5 types: “exonic”, “intronic”, “antisense”, “sense overlapping” and “intergenic”; FC absolute ratio (no log scale) of normalized intensities between two conditions; p-value p-value calculated from unpaired t-test; Annotations, include chromosome position and Gene Symbol

ISSN: 2045-3701