Skip to main content
Fig. 3 | Cell & Bioscience

Fig. 3

From: Dynorphin activation of kappa opioid receptor promotes microglial polarization toward M2 phenotype via TLR4/NF-κB pathway

Fig. 3

PDYN overexpression inhibited pilocarpine-induced TLR4/NF-κB pathway in a rat model of epilepsy. a The serum levels of M1-related pro-inflammatory cytokines (IL-1β and IL-6) and M2-related cytokines (IL-4 and IL-10) in rats were examined by ELISA. b The protein levels of TLR4, IκB-α, p-IκB-α, NF-κB p65, and p-NF-κB p65 were examined by western blot. n = 8/group. **p < 0.01, vs. Control group, ##p < 0.01, vs. LV-NC group

Back to article page

Cell & Bioscience

ISSN: 2045-3701

Contact us