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Fig. 5 | Cell & Bioscience

Fig. 5

From: Insights into superoxide dismutase 3 in regulating biological and functional properties of mesenchymal stem cells

Fig. 5

The role of MSCs-secreted SOD3. MSCs secreted SOD3 found to increase the survival of neuronal cells, neutrophils and cardiomyocytes when co-cultured under stress conditions. The SOD3 secreted by MSCs also found to regulate cancer progression. SOD3 found to modulate the phenotypic and functional properties of MSCs. SOD3 superoxide dismutase 3, MSCs mesenchymal stem cells, Pi3K Phosphoinositide 3-kinases, Akt protein kinase B, ERK extracellular signal-regulated kinase, NRF2 Nuclear factor erythroid 2-related factor 2, FoxO1 Forkhead box O1

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