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Fig. 1 | Cell & Bioscience

Fig. 1

From: Dose-dependent roles of aspirin and other non-steroidal anti-inflammatory drugs in abnormal bone remodeling and skeletal regeneration

Fig. 1

The roles of low-dose aspirin in the regulation of bone remodeling. Aspirin at low dosage might suppress the differentiation of osteoclasts and promotes the bone formation via osteoblastic cells. The solid red arrows indicate the promotion of cellular processes, and the solid green lines indicate inhibition of cellular processes. The dotted lines indicate that the mechanism has not been fully elucidated. HSC hematopoietic stem cells, MSC mesenchymal stem cells, T cell T lymphocytes, Pre-OC precursors of osteoclasts, Pre-OB precursors of osteoblasts, OPG osteoprotegerin

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