Fig. 5

PRC1 regulated GLI1 expression in association with the Wnt/β-catenin signaling pathway. a The effect of PRC1 and Wnt3a on mRNAs expression of survivin, MYC and JUN in activated HSCs. **Represents Wnt3a (−) + shPRC1 vs. Wnt3a (−) + shNC, p < 0.01. ##Represents Wnt3a (+) + shPRC1 vs. Wnt3a (+) + shNC, p < 0.01. b The effect of PRC1 and Wnt3a on proteins expression of PRC1, β-catenin, active β-catenin and GLI1 in activated HSCs. **Represents Wnt3a (−) + shPRC1 vs. Wnt3a (−) + shNC, p < 0.01. ##Represents Wnt3a (+) + shPRC1 vs. Wnt3a (+) + shNC, p < 0.01