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Fig. 5 | Cell & Bioscience

Fig. 5

From: PRC1 promotes GLI1-dependent osteopontin expression in association with the Wnt/β-catenin signaling pathway and aggravates liver fibrosis

Fig. 5

PRC1 regulated GLI1 expression in association with the Wnt/β-catenin signaling pathway. a The effect of PRC1 and Wnt3a on mRNAs expression of survivin, MYC and JUN in activated HSCs. **Represents Wnt3a (−) + shPRC1 vs. Wnt3a (−) + shNC, p < 0.01. ##Represents Wnt3a (+) + shPRC1 vs. Wnt3a (+) + shNC, p < 0.01. b The effect of PRC1 and Wnt3a on proteins expression of PRC1, β-catenin, active β-catenin and GLI1 in activated HSCs. **Represents Wnt3a (−) + shPRC1 vs. Wnt3a (−) + shNC, p < 0.01. ##Represents Wnt3a (+) + shPRC1 vs. Wnt3a (+) + shNC, p < 0.01

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