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Table 4 MiRNAs and their downregulated mRNA targets in the blood–brain barrier clearance of Aβ

From: Potential microRNA-related targets in clearance pathways of amyloid-β: novel therapeutic approach for the treatment of Alzheimer’s disease

MiRNAFamilyGeneReferences
miR-185, miR-328-5pReceptor for advanced glycation end productsRAGE[220, 221]
miR-205Low-density lipoprotein receptorsLRP1[222]
miR-148b LRP2[223]
miR-26, miR-19b, miR-302aATP-binding cassette transportersABCA1[224,225,226]
miR-200c, miR-873, miR-491-3p, miR-223 ABCB1[227,228,229,230]
miR-328, miR-302, miR-3163, miR-181a ABCG2[231,232,233,234]
miR-185-5p, miR-463-3p ABCG4[235, 236]
miR-29b, miR-130bGlymphatic clearanceAQP4[237, 238]