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Fig. 2 | Cell & Bioscience

Fig. 2

From: Long noncoding RNA CASC2 suppresses esophageal squamous cell carcinoma progression by increasing SOCS1 expression

Fig. 2

CASC2 suppresses ESCC cell proliferation, migration and invasion. a The expression levels of lncRNA CASC2 in different ESCC cell lines. b CASC2 was overexpressed in KYSE30 and KYSE150 cells. The CASC2 overexpression efficacy was confirmed by real-time PCR. c The effect of CASC2 overexpression on the proliferation of KYSE30 and KYSE150 cells was detected by CCK-8 assay. d The colony formation number of control and CASC2 overexpressing KYSE30 and KYSE150 cells. e CASC2 was knocked down in KYSE30 and KYSE150 cells. The CASC2 knockdown efficacy was confirmed by real-time PCR. f The effect of CASC2 knockdown on the proliferation of KYSE30 and KYSE150 cells was detected by CCK-8 assay. g The colony formation number of control and CASC2 silencing KYSE30 and KYSE150 cells. h Migration and invasion assays of KYSE30 and KYSE150 cells with CASC2 overexpression by Transwell assay (quantification in right histogram). i Migration and invasion assays of KYSE30 and KYSE150 cells with CASC2 knockdown by Transwell assay (quantification in right histogram). Error bars indicate SD. *p < 0.05

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