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Fig. 4 | Cell & Bioscience

Fig. 4

From: Babao Dan attenuates acute ethanol-induced liver injury via Nrf2 activation and autophagy

Fig. 4

Nrf2 activation contributes BBD-mediated hepatoprotective effect. a Western blotting analysis of Nrf2 and the two transcriptional targets of HO-1 and GCLC expression in response to BBD (0.5 g/kg BW) alone. b Real-time PCR analysis of Nrf2 and the two downstream targets of HO-1 and GCLC transcription reacted to BBD treatment alone. Effects of BBD on related genes expression in c protein and d transcriptional level in liver. Experiments were repeated three times. Data were expressed as mean ± SD; #P < 0.05, ##P < 0.01 compared to control; *P < 0.05, **P < 0.01 compared to NS + EtOH group; ^P < 0.05. EtOH ethanol, 0.125 BBD 0.125 mg/kg BBD, 0.25 BBD 0.25 mg/kg BBD, 0.5 BBD 0.5 mg/kg

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