Fig. 3From: Metformin represses the pathophysiology of AAA by suppressing the activation of PI3K/AKT/mTOR/autophagy pathway in ApoE−/− miceMetformin attenuates Ang-II-induced activation of PI3K/AKT/mTOR pathway and the expression of LC3B and Beclin1 in ApoE−/−mice. Immunohistochemistry staining was used to observe the expression of PI3K, AKT, mTOR, LC3B and Beclin1, and the phosphorylation levels of PI3K, AKT and mTOR in aortic tissueBack to article page