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Table 1 The potential transcriptional factors binding to DUSP8 promoter

From: DUSP8 phosphatase: structure, functions, expression regulation and the role in human diseases

Transcription factors Numbers of probable binding sites Representative binding sites (5′–3′) RE equally RE query
PAX5 14 CCAGCCC (− 1936 to − 1930 bp) 1.09918 3.98542
GGGCAGG (− 1688 to − 1682 bp)
GATA1 1 TATCTG (− 1921 to − 1916 bp) 0.48853 0.20125
ERα 12 TGACC (− 1894 to − 1890 bp) 1.9541 2.1066
GGTCA (− 1856 to − 1852 bp)
YY1 18 CCAT (− 1840 to − 1837 bp) 7.81641 6.50071
ATGG (− 1796 to − 1793 bp)
GRα 12 CCTGT (− 1957 to – 1953 bp) 3.9082 3.2513
ACAGG (− 1805 to − 1801 bp)
p53 5 GGGCAGG (− 1688 to − 1682 bp) 0.24426 0.629
CCTGCCC (− 1669 to − 1663 bp)
C/EBPβ 19 GCAA (− 1879 to − 1876 bp) 15.63281 10.04412
TTGC (− 1615 to − 1612 bp)
TFII-I 5 CTGTCC (− 1531 to − 1526 bp) 1.46558 1.42439
GGACAG (− 547 to − 542 bp)
c-ETS1 2 CTTCCTG (− 1338 to − 1332 bp) 0.12213 0.12024
CAGGAAG (− 361 to – 355 bp)
AP-2α 6 GCCTGC (− 1522 to − 1517 bp) 0.48853 1.25819
GCAGGC (− 1071 to − 1066 bp)
SP1 1 GCCCCGCCCC (− 931 to − 922 bp) 0.00191 0.02559
c-Myc 1 CACGTG (− 801 to − 796 bp) 0.48853 0.68269
GRβ 1 AATGT (− 403 to − 399 bp) 3.9082 0.95709
RXRα 1 TGAACCC (− 377 to − 371 bp) 0.24426 0.18531
GCF 1 TCCCAGCGC (− 82 to − 74 bp) 0.0916 0.61911
IRF2 1 TCACTT (− 39 to − 34 bp) 0.48853 0.20114