Table 1 The potential transcriptional factors binding to DUSP8 promoter
From: DUSP8 phosphatase: structure, functions, expression regulation and the role in human diseases
Transcription factors | Numbers of probable binding sites | Representative binding sites (5′–3′) | RE equally | RE query |
|---|---|---|---|---|
PAX5 | 14 | CCAGCCC (− 1936 to − 1930 bp) | 1.09918 | 3.98542 |
GGGCAGG (− 1688 to − 1682 bp) | ||||
GATA1 | 1 | TATCTG (− 1921 to − 1916 bp) | 0.48853 | 0.20125 |
ERα | 12 | TGACC (− 1894 to − 1890 bp) | 1.9541 | 2.1066 |
GGTCA (− 1856 to − 1852 bp) | ||||
YY1 | 18 | CCAT (− 1840 to − 1837 bp) | 7.81641 | 6.50071 |
ATGG (− 1796 to − 1793 bp) | ||||
GRα | 12 | CCTGT (− 1957 to – 1953 bp) | 3.9082 | 3.2513 |
ACAGG (− 1805 to − 1801 bp) | ||||
p53 | 5 | GGGCAGG (− 1688 to − 1682 bp) | 0.24426 | 0.629 |
CCTGCCC (− 1669 to − 1663 bp) | ||||
C/EBPβ | 19 | GCAA (− 1879 to − 1876 bp) | 15.63281 | 10.04412 |
TTGC (− 1615 to − 1612 bp) | ||||
TFII-I | 5 | CTGTCC (− 1531 to − 1526 bp) | 1.46558 | 1.42439 |
GGACAG (− 547 to − 542 bp) | ||||
c-ETS1 | 2 | CTTCCTG (− 1338 to − 1332 bp) | 0.12213 | 0.12024 |
CAGGAAG (− 361 to – 355 bp) | ||||
AP-2α | 6 | GCCTGC (− 1522 to − 1517 bp) | 0.48853 | 1.25819 |
GCAGGC (− 1071 to − 1066 bp) | ||||
SP1 | 1 | GCCCCGCCCC (− 931 to − 922 bp) | 0.00191 | 0.02559 |
c-Myc | 1 | CACGTG (− 801 to − 796 bp) | 0.48853 | 0.68269 |
GRβ | 1 | AATGT (− 403 to − 399 bp) | 3.9082 | 0.95709 |
RXRα | 1 | TGAACCC (− 377 to − 371 bp) | 0.24426 | 0.18531 |
GCF | 1 | TCCCAGCGC (− 82 to − 74 bp) | 0.0916 | 0.61911 |
IRF2 | 1 | TCACTT (− 39 to − 34 bp) | 0.48853 | 0.20114 |