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Fig. 2 | Cell & Bioscience

Fig. 2

From: Combination chemotherapy of valproic acid (VPA) and gemcitabine regulates STAT3/Bmi1 pathway to differentially potentiate the motility of pancreatic cancer cells

Fig. 2

Combination of gemcitabine and VPA regulates Bmi1 expression. PANC-1 and Patu8988 cells were pretreated with 0.5 mM or 5 mM of VPA for 12 h and then cotreated with 5 μm of gemcitabine for 24 h. a The protein level of Bmi1 was measured by western blot analysis. b The nuclear accumulation of Bmi1 was determined by immunofluorescence. The graphs are representative results of three independently repeated experiments

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