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Fig. 2 | Cell & Bioscience

Fig. 2

From: Label-free quantitative proteomics identifies transforming growth factor β1 (TGF-β1) as an inhibitor of adipogenic transformation in OP9-DL1 cells and primary thymic stromal cells

Fig. 2

TGF-β1 attenuated rosiglitazone-induced adipogenic differentiation in OP9-DL1 cells. OP9-DL1 cells were treated with various concentrations of TGF-β1 for 7 days in the presence of rosiglitazone. a Lipid accumulation was visualized by Oil Red O staining, and representative photographs of accumulated lipids are shown. b Real-time PCR was performed to detect FABP4 and PPARγ mRNA levels. The data were normalized to GAPDH, and the graph represents the results of three independent experiments. **P < 0.01; *P < 0.05. c OP9-DL1 cells were treated with rosiglitazone and TGF-β1 in the presence of LY-364947 for 7 days. Representative images of accumulated lipids in differentiating OP9-DL1 cells visualized by Oil Red O staining are presented. Bars, 50 μM. Rosi rosiglitazone

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