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Table 5 Distribution of genotypic frequencies along with inheritance models of MBL2 5′ additional variants in RVVI cases and controls

From: Impact of SNPs interplay across the locus of MBL2, between MBL and Dectin-1 gene, on women’s risk of developing recurrent vulvovaginal infections

Genetic models Genotype VVI cases Controls OR (95% CI) p-value AIC BIC
(N = 258) (N = 203)
Freq (%) Freq (%)
rs11003124
 Codominant T/T 155 (60.11) 125 (61.60) 1.00    
T/G 90 (34.92) 64 (31.50) 1.14 (0.76–1.69) 0.53 639.4 655.9
G/G 13 (5.00) 14 (6.90) 0.75 (0.34–1.65) 0.58   
 Dominant T/T 155 (60.10) 125 (61.60) 1.00    
T/G-G/G 103 (39.91) 78 (38.41) 1.07 (0.73–1.56) 0.74 638.4 650.8
 Recessive T/T-T/G 245 (95.23) 189 (93.12) 1.00    
G/G 13 (5.00) 14 (6.90) 0.72 (0.33–1.56) 0.4 637.8 650.2
 Overdominant T/T-G/G 168 (65.10) 139 (68.50) 1.00    
T/G 90 (34.90) 64 (31.50) 1.17 (0.79–1.73) 0.45 637.9 650.3
 Log-additive 0.99 (0.73–1.34) 0.95 638.5 650.9
rs7084554
 Codominant T/T 147 (56.97) 143 (70.42) 1.00    
T/C 95 (36.82) 49 (24.11) 1.90 (1.25–2.89) 0.002* 631 647.6
C/C 16 (6.21) 11 (5.42) 1.41 (0.63–3.15) 0.396   
 Dominant T/T 147 (57.21) 143 (70.41) 1.00    
T/C-C/C 111 (43.12) 60 (29.60) 1.81 (1.22–2.68) 0.002* 629.5 641.9
 Recessive T/T-T/C 242 (93.80) 192 (94.60) 1.00    
C/C 16 (6.21) 11 (5.41) 1.15 (0.52–2.55) 0.72 638.4 650.8
 Overdominant T/T-C/C 163 (63.21) 154 (75.90) 1.00    
T/C 95 (36.81) 49 (24.12) 1.85 (1.22–2.79) 0.003* 629.7 642.1
 Log-additive 1.50 (1.09–2.07) 0.01* 632 644.4
rs36014597
 Codominant A/A 110 (42.60) 147 (72.41) 1.00    
A/G 136 (52.70) 44 (21.70) 4.20 (2.75–6.41) 1.08 × 10−10** 592 608.5
G/G 12 (4.70) 12 (5.90) 1.33 (0.57–3.08) 0.497   
 Dominant A/A 110 (42.60) 147 (72.41) 1.00    
A/G-G/G 148 (57.42) 56 (27.60) 3.61 (2.42–5.38) 8.8 × 10−10** 596 608.4
 Recessive A/A-A/G 246 (95.31) 191 (94.12) 1.00    
G/G 12(4.70) 12 (5.90) 0.77 (0.34–1.77) 0.54 638.1 650.5
 Overdominant A/A-G/G 122 (47.31) 159 (78.32) 1.00    
A/G 136 (52.70) 44 (21.70) 4.07 (2.69–6.17) 1.1 × 10−10** 590.5 602.9
 Log-additive 2.42(1.72–3.41) 1.2 × 10−6** 610.8 623.2
rs11003123
 Codominant G/G 100 (38.81) 84 (41.42) 1.00    
G/A 143 (55.41) 104 (51.22) 1.16(0.79–1.70) 0.46 639.5 656
A/A 15 (5.82) 15 (7.41) 0.84 (0.39–1.82) 0.61   
 Dominant G/G 100 (38.81) 84 (41.42) 1.00    
G/A-A/A 158 (61.22) 119 (58.61) 1.12 (0.77–1.62) 0.57 638.2 650.6
 Recessive G/G-G/A 243 (94.22) 188 (92.61) 1.00    
A/A 15 (5.81) 15 (7.40) 0.77 (0.37–1.62) 0.5 638 650.4
 Overdominant G/G-A/A 115 (44.61) 99 (48.80) 1.00    
G/A 143 (55.41) 104 (51.21) 1.18 (0.82–1.71) 0.37 637.7 650.1
 Log-additive 1.03 (0.76–1.40) 0.85 638.5 650.9
  1. Italics values indicate low AIC/BIC value
  2. AIC Akaike’s Information Criterion, BIC Bayesian Information Criterion
  3. * Indicates (p ≤ 0.01)
  4. ** Indicates (p ≤ 0.001)