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Table 11 Distribution of sMBL levels in cases and controls, stratified on the basis of combined 5′/3′ block haplotypes of MBL2

From: Impact of SNPs interplay across the locus of MBL2, between MBL and Dectin-1 gene, on women’s risk of developing recurrent vulvovaginal infections

Haplotypes Controls RVVI p-value (controls vs RVVI) BV p-value (controls vs BV) VVC p-value (controls vs VVC) MI p-value (controls vs MI)
n Mean ± SD n Mean ± SD n Mean ± SD n Mean ± SD n Mean ± SD
5′H-10/3′H-2 24 836.70 ± 293.17 23 434.33 ± 190.36ab 1.7 × 10−6*** 9 466.93 ± 253.23 0.002** 8 348.26 ± 113.77 1.9 × 10−7*** 6 502.68 ± 148.28d 0.001***
5′H-5/3′H-1 12 957.48 ± 453.28 16 857.95 ± 549.84a 0.614 9 976.38 ± 598.13 0.935 3 296.06 ± 345.25 0.036* 4 1042.5 ± 282.10d e 0.733
5′H-3/3′H-3 15 1267.1 ± 418.30 10 714.96 ± 513.21 0.007** 4 792.13 ± 657.76 0.090 3 541.73 ± 635.47 0.02* 3 785.30 ± 260.96 0.076
5′H-1/3′H-1 14 1261.6 ± 612.37 10 795.10 ± 425.08 0.050* 10 795.10 ± 425.08 0.050* 0 0.00 ± 0.00 NA 0 0.00 ± 0.00 NA
5′H-9/3′H-1 15 1228.8 ± 545.30 8 729.92 ± 407.04 0.034* 4 788.98 ± 463.87 0.160 2 796.85 ± 645.86 NA 2 544.88 ± 75.72 NA
5′H-1/3′H-2 9 999.78 ± 162.15 11 969.51 ± 530.29bc 0.861 4 1113.4 ± 138.52 0.251 5 934.80 ± 788.63 0.864 2 768.50 ± 311.79 NA
5′H-35/3′H-3 4 1070.9 ± 362.48 11 389.29 ± 194.90c 3.6 × 10−4*** 5 363.78 ± 281.19 0.013* 3 346.46 ± 51.56 0.026* 3 466.14 ± 127.39e 0.042*
5′H-60/3′H-1 3 915.49 ± 320.84 11 735.61 ± 320.19 0.405 7 578.27 ± 174.35 0.057 3 576.38 ± 110.23 0.158 1 1159.05 ± 0.00 NA
p-value††   0.032*   0.002**    0.050*    0.269    0.006**  
  1. Haplotypes with n < 3 are not included in statistical analysis
  2. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001
  3. Independent t-test between patients and controls as well as within groups
  4. ††One Way ANOVA with overall p-value followed by Post Hoc Tukey test that further indicates values with similar letter are significantly different
  5. ap = 0.033, b p = 0.010, c p = 0.021, d p = 0.008, e p = 0.016