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Table 11 Distribution of sMBL levels in cases and controls, stratified on the basis of combined 5′/3′ block haplotypes of MBL2

From: Impact of SNPs interplay across the locus of MBL2, between MBL and Dectin-1 gene, on women’s risk of developing recurrent vulvovaginal infections

Haplotypes

Controls

RVVI

p-value (controls vs RVVI)

BV

p-value (controls vs BV)

VVC

p-value (controls vs VVC)

MI

p-value (controls vs MI)

n

Mean ± SD

n

Mean ± SD

n

Mean ± SD

n

Mean ± SD

n

Mean ± SD

5′H-10/3′H-2

24

836.70 ± 293.17

23

434.33 ± 190.36ab

1.7 × 10−6***

9

466.93 ± 253.23

0.002**

8

348.26 ± 113.77

1.9 × 10−7***

6

502.68 ± 148.28d

0.001***

5′H-5/3′H-1

12

957.48 ± 453.28

16

857.95 ± 549.84a

0.614

9

976.38 ± 598.13

0.935

3

296.06 ± 345.25

0.036*

4

1042.5 ± 282.10d e

0.733

5′H-3/3′H-3

15

1267.1 ± 418.30

10

714.96 ± 513.21

0.007**

4

792.13 ± 657.76

0.090

3

541.73 ± 635.47

0.02*

3

785.30 ± 260.96

0.076

5′H-1/3′H-1

14

1261.6 ± 612.37

10

795.10 ± 425.08

0.050*

10

795.10 ± 425.08

0.050*

0

0.00 ± 0.00

NA

0

0.00 ± 0.00

NA

5′H-9/3′H-1

15

1228.8 ± 545.30

8

729.92 ± 407.04

0.034*

4

788.98 ± 463.87

0.160

2

796.85 ± 645.86

NA

2

544.88 ± 75.72

NA

5′H-1/3′H-2

9

999.78 ± 162.15

11

969.51 ± 530.29bc

0.861

4

1113.4 ± 138.52

0.251

5

934.80 ± 788.63

0.864

2

768.50 ± 311.79

NA

5′H-35/3′H-3

4

1070.9 ± 362.48

11

389.29 ± 194.90c

3.6 × 10−4***

5

363.78 ± 281.19

0.013*

3

346.46 ± 51.56

0.026*

3

466.14 ± 127.39e

0.042*

5′H-60/3′H-1

3

915.49 ± 320.84

11

735.61 ± 320.19

0.405

7

578.27 ± 174.35

0.057

3

576.38 ± 110.23

0.158

1

1159.05 ± 0.00

NA

p-value††

 

0.032*

 

0.002**

  

0.050*

  

0.269

  

0.006**

 
  1. Haplotypes with n < 3 are not included in statistical analysis
  2. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001
  3. Independent t-test between patients and controls as well as within groups
  4. ††One Way ANOVA with overall p-value followed by Post Hoc Tukey test that further indicates values with similar letter are significantly different
  5. ap = 0.033, b p = 0.010, c p = 0.021, d p = 0.008, e p = 0.016