Fig. 4From: CRISPR Cpf1 proteins: structure, function and implications for genome editingSchematic representation of the Cpf1-gRNA/tRNA expression structure. a Secondary cloverleaf structure of the eukaryotic pre-tRNA. In the process of tRNA maturation it can be cleaved by RNase P and RNase Z at specific sites. b Structure of Cpf1 gRNA/tRNA system with U6/T7 promoter-gRNA-tRNA. c Multiplex gRNA/tRNA systemBack to article page