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Fig. 2 | Cell & Bioscience

Fig. 2

From: The Y-linked proto-oncogene TSPY contributes to poor prognosis of the male hepatocellular carcinoma patients by promoting the pro-oncogenic and suppressing the anti-oncogenic gene expression

Fig. 2

Transcriptome and DAVID analyses of the HuH-7-tetOn-TSPY cells. a MA-plots showing the differentially expressed genes (DEGs) between HuH-7-tetOn-TSPY cells and HuH-7-tetOn-EGFP cells. Genes plotted within the areas of Log2[expression level] > 3.32 and |log2[fold change]| > 0.6 (red) were analyzed as differentially expressed genes (DEGs). b DAVID gene-annotation enrichment analysis identified top 5 KEGG pathways enriched in DEGs with FDR < 0.05; FDR = false discovery rate or corrected P-value. c Mapping of the 26 DEGs on the KEGG cell-cycle pathway [49]. Red indicates the upregulated genes and green indicates the downregulated genes in the Dox-treated HuH-7-tetON-TSPY cells

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