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Table 4 Descriptive analysis of survivors versus non-survivors at 2 years

From: Short-term and long-term outcomes of liver resection for HCC patients with portal vein tumor thrombus

Variable

Alive

(n = 98)

Died

(n = 291)

P

Age, years

48.9 ± 11.1

47.7 ± 10.4

0.368

Sex

1.000

 Female

11 (11.2%)

34 (11.7%)

 

 Male

87 (88.8%)

257 (88.3%)

 

Viral marker

 HBsAg positive

87 (89.7%)

266 (92.4%)

0.541

 Anti-HCV positive

0 (0.0%)

2 (0.7%)

1.000

AFP, μg/L

763 (1.2–138,410)

1210 (1.8–777,600)

0.012

AFP, Log 10 μg/L

2.88 (0.08–5.14)

3.08 (0.26–5.89)

0.012

TBIL, mg/dL

0.77 (0.26–1.87)

0.85 (0.30–7.54)

0.024

ALB, g/L

41.6 (17.2–67.2)

40.8 (17.8–65.3)

0.421

PT, s

12.1 (9.9–14.9)

12.4 (9.6–18.0)

0.054

ALT, U/L

42.8 (11.2–187.8)

43.0 (8.7–169.9)

0.875

PLT, 109/L

172 (25.0–405)

151 (25.0–629)

0.148

WBC, 109/L

5.57 (1.80–10.4)

5.44 (1.44–19.4)

0.672

Hemoglobin, g/L

140 (104–174)

141 (75.0–195)

0.984

Child–Pugh class

0.460

 A

97 (99.0%)

283 (97.3%)

 

 B

1 (1.0%)

8 (2.7%)

 

Radiologic ascites

0.110

 No

94 (95.9%)

262 (90.0%)

 

 Mild

4 (4.1%)

29 (10.0%)

 

Gastroesophageal varices

0.155

 No

88 (89.8%)

242 (83.2%)

 

 Yes

10 (10.2%)

49 (16.8%)

 

Radiologic spleen length, cm

11.0 (6.3–16.4)

11.7 (6.3–20.2)

0.005

CSPH

0.010

 No

60 (61.2%)

138 (47.4%)

 

 Mild

36 (36.7%)

124 (42.6%)

 

 Severe

2 (2.1%)

29 (10.0%)

 

Type of hepatectomy

0.130

 En bloc resection

56 (57.1%)

193 (66.3%)

 

 Non-en bloc resection

42 (42.9%)

98 (33.7%)

 

Operating time, h

2.0 (0.45–20.8)

2.0 (0.45–10.3)

0.488

Hilar clamping time, min

21.0 (0–58.0)

20.0 (0–83.0)

0.334

Intraoperative blood loss, mL

325 (100–3200)

400 (0–45,000)

0.038

Transfusion

0.409

 No

73 (74.5%)

202 (69.4%)

 

 Yes

25 (25.5%)

89 (30.6%)

 

Surgical margins

0.690

 R0

81 (82.7%)

227 (78.0%)

 

 R1

2 (2.0%)

9 (3.1%)

 

 Unconfirmed

15 (15.3%)

55 (18.9%)

 

Extent of PVTT

0.115

 Left branch

22 (22.4%)

69 (23.7%)

 

 Right branch

62 (63.3%)

154 (52.9%)

 

 Main trunck/contralateral branch

14 (14.3%)

68 (23.4%)

 

Tumor number

0.781

 Solitary

88 (89.8%)

266 (91.4%)

 

 Multiple

10 (10.2%)

25 (8.59%)

 

Tumor diameter, cm

7.7 (2.0–18.2)

8.8 (0.4–24.0)

0.049

Cirrhosis

0.067

 No

35 (35.7%)

74 (25.4%)

 

 Yes

63 (64.3%)

217 (74.6%)

 

Tumor differentiation

0.007

 II

11 (11.2%)

9 (3.09%)

 

 III

85 (86.7%)

277 (95.2%)

 

 IV

2 (2.1%)

5 (1.72%)

 
  1. HBsAg hepatitis B surface antigen, anti-HCV hepatitis C virus antibody, AFP α-fetoprotein, TBIL total bilirubin, ALB albumin, PT pro-thrombin time, ALT alanine aminotransferase, PLT platelet count, WBC white blood cell, CSPH clinical significant portal hypertension, PVTT portal vein tumor thrombus