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Table 2 Descriptive analysis of survivors versus non-survivors at 3 months

From: Short-term and long-term outcomes of liver resection for HCC patients with portal vein tumor thrombus

Variable

Alive

(n = 405)

Died

(n = 51)

P

Age, years

47.8 ± 10.2

48.9 ± 10.6

0.453

Sex

1.000

 Female

44 (10.9%)

6 (11.8%)

 

 Male

361 (89.1%)

45 (88.2%)

 

Viral marker

 HBsAg positive

370 (92.0%)

49 (98.0%)

0.156

 Anti-HCV positive

3 (0.7%)

0 (0.0%)

1.000

AFP, μg/L

1210 (1.2–276,354)

1210 (2.9–777,600)

0.003

AFP, Log 10 μg/L

3.08 (0.08–5.44)

3.08 (0.46–5.89)

0.003

TBIL, mg/dL

0.79 (0.26–7.54)

0.94 (0.34–7.54)

< 0.001

ALB, g/L

40.9 (17.2–67.2)

41.6 (32.4–65.3)

0.799

PT, s

12.2 (9.6–18.0)

12.4 (10.7–18.0)

0.121

ALT, U/L

43.3 (8.7–187.8)

41.3 (9.3–162.1)

0.853

PLT, 109/L

157 (25.0–629)

139 (63.0–358)

0.452

WBC, 109/L

5.51 (1.44–19.4)

5.41 (2.29–10.6)

0.964

Hemoglobin, g/L

141 (94.0–195.0)

146 (75.0–172.0)

0.085

Child–Pugh class

0.266

 A

398 (98.3%)

49 (96.1%)

 

 B

7 (1.7%)

2 (3.9%)

 

Radiologic ascites

0.003

 No

380 (93.8%)

41 (80.4%)

 

 Mild

25 (6.2%)

10 (19.6%)

 

Gastroesophageal varices

0.397

 No

341 (84.2%)

40 (78.4%)

 

 Yes

64 (15.8%)

11 (21.6%)

 

Radiologic spleen length, cm

11.3 (6.3–20.2)

12.0 (8.0–18.9)

0.029

CSPH

0.194

 No

212 (52.3%)

20 (39.2%)

 

 Mild

157 (38.8%)

26 (51.0%)

 

 Severe

36 (8.9%)

5 (9.8%)

 

Type of hepatectomy

0.327

 Enbloc

253 (62.5%)

36 (70.6%)

 

 Non-enbloc

152 (37.5%)

15 (29.4%)

 

Operating time, h

2.0 (0.45–20.8)

2.0 (0.45–5.7)

0.862

Hilar clamping time, min

20.0 (0–83.0)

20.0 (0–51.0)

0.474

Intraoperative blood loss, mL

400 (0–45,000)

400 (0–8000)

0.598

Transfusion

0.544

 No

291 (71.9%)

34 (66.7%)

 

 Yes

114 (28.1%)

17 (33.3%)

 

Surgical margins

1.000

 R0

321 (79.3%)

42 (82.3%)

 

 R1

15 (3.7%)

1 (2.0%)

 

 Unconfirmed

69 (17.0%)

8 (15.7%)

 

Extent of PVTT

0.281

 Left branch

95 (23.5%)

7 (13.7%)

 

 Right branch

224 (55.3%)

31 (60.8%)

 

 Main trunck/contralateral branch

86 (21.2%)

13 (25.5%)

 

Tumor number

1.000

 Solitary

366 (90.4%)

46 (90.2%)

 

 Multiple

39 (9.6%)

5 (9.8%)

 

Tumor diameter, cm

8.0 (0.6–22.0)

10.0 (0.4–24.0)

0.023

Cirrhosis

0.173

 No

121 (29.9%)

10 (19.6%)

 

 Yes

284 (70.1%)

41 (80.4%)

 

Tumor differentiation

0.612

 II

23 (5.7%)

1 (2.0%)

 

 III

375 (92.6%)

49 (96.0%)

 

 IV

7 (1.7%)

1 (2.0%)

 
  1. HBsAg hepatitis B surface antigen, anti-HCV hepatitis C virus antibody, AFP α-fetoprotein, TBIL total bilirubin, ALB albumin, PT pro-thrombin time, ALT alanine aminotransferase, PLT platelet count, WBC white blood cell, CSPH clinical significant portal hypertension, PVTT portal vein tumor thrombus