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Table 1 Baseline characteristics for all patients

From: Short-term and long-term outcomes of liver resection for HCC patients with portal vein tumor thrombus

Variable Overall (N = 457) Alive (n = 139) Died (n = 318) P
Age, years 47.9 ± 10.3 47.6 ± 9.38 48.1 ± 10.7 0.612
Sex 0.378
 Female 50 (10.9%) 12 (8.6%) 38 (11.9%)  
 Male 407 (89.1%) 127 (91.4%) 280 (88.1%)  
Viral marker     
 HBsAg positive 420 (92.7%) 131 (94.2%) 289 (92.0%) 0.524
 Anti-HCV positive 3 (0.7%) 1 (0.7%) 2 (0.6%) 1.000
AFP, μg/L 1210 (1.2–777,600) 1067 (1.2–37,073) 1210 (1.8–777,600) 0.034
AFP, Log 10 μg/L 3.08 (0.08–5.89) 3.03 (0.08–4.57) 3.08 (0.26–5.89) 0.034
TBIL, mg/dL 0.81 (0.26–7.54) 0.77 (0.26–1.87) 0.83 (0.30–7.54) 0.023
ALB, g/L 41.0 (17.2–67.2) 41.3 (17.2–67.2) 40.8 (17.8–65.3) 0.169
PT, s 12.2 (9.6–18.0) 12.2 (10.2–15.2) 12.3 (9.6–18.0) 0.411
ALT, U/L 42.6 (8.7–187.8) 42.1 (11.2–187.8) 42.7 (8.7–169.9) 0.965
PLT, 109/L 156 (25.0–629) 156 (25.0–369) 156 (25.0–629) 0.957
WBC, 109/L 5.51 (1.44–19.4) 5.40 (1.63–11.8) 5.54 (1.44–19.4) 0.187
Hemoglobin, g/L 141 (75.0–195.0) 142 (104.0–174.0) 141 (75.0–195.0) 0.988
Child–Pugh class 0.288
 A 448 (98.0%) 138 (99.3%) 310 (97.5%)  
 B 9 (2.0%) 1 (0.7%) 8 (2.5%)  
Radiologic ascites 0.019
 No 422 (92.3%) 135 (97.1%) 287 (90.3%)  
 Mild 35 (7.66%) 4 (2.88%) 31 (9.75%)  
Gastroesophageal varices 1.000
 No 382 (83.6%) 116 (83.5%) 266 (83.6%)  
 Yes 75 (16.4%) 23 (16.5%) 52 (16.4%)  
Radiologic spleen length, cm 11.4 (6.30–20.2) 11.0 (6.30–17.5) 11.6 (6.30–20.2) 0.060
CSPH 0.237
 No 233 (51.0%) 79 (56.8%) 154 (48.4%)  
 Mild 183 (40.0%) 48 (34.5%) 135 (42.5%)  
 Severe 41 (9.0%) 12 (8.6%) 29 (9.1%)  
Type of hepatectomy 0.177
 En bloc resection 289 (63.2%) 81 (58.3%) 208 (65.4%)  
 Non-en bloc resection 168 (36.8%) 58 (41.7%) 110 (34.6%)  
Operating time, h 2.0 (0.45–20.8) 2.0 (0.45–20.8) 2.0 (0.45–20.8) 0.175
Hilar clamping time, min 20.0 (0–83.0) 21.0 (0–48.0) 20.0 (0–83.0) 0.248
Intraoperative blood loss, mL 400 (0–45,000) 400 (10–3200) 400 (0–45,000) 0.181
Transfusion 0.229
 No 326 (71.3%) 105 (75.5%) 221 (69.5%)  
 Yes 131 (28.7%) 34 (24.5%) 97 (30.5%)  
Surgical margins 0.115
 R0 363 (79.4%) 115 (82.7%) 248 (78.0%)  
 R1 16 (3.5%) 7 (5.1%) 9 (2.8%)  
 Unconfirmed 78 (17.1%) 17 (12.2%) 61 (19.2%)  
Extent of PVTT 0.523
 Left branch 102 (22.3%) 27 (19.4%) 75 (23.6%)  
 Right branch 256 (56.0%) 83 (59.7%) 173 (54.4%)  
 Main trunck/contralateral branch 99 (21.7%) 29 (20.9%) 70 (22.0%)  
Tumor number 0.283
 Solitary 413 (90.4%) 122 (87.8%) 291 (91.5%)  
 Multiple 44 (9.6%) 17 (12.2%) 27 (8.49%)  
Tumor diameter, cm 8.3 (0.4–24.0) 7.5 (0.6–22.0) 9.0 (0.4–24.0) 0.004
Cirrhosis 0.295
 No 131 (28.7%) 45 (32.4%) 86 (27.0%)  
 Yes 326 (71.3%) 94 (67.6%) 232 (73.0%)  
Tumor differentiation 0.647
 II 24 (5.3%) 9 (6.5%) 15 (4.7%)  
 III 425 (93.0%) 127 (91.4%) 298 (93.7%)  
 IV 8 (1.7%) 3 (2.1%) 5 (1.6%)  
  1. HBsAg hepatitis B surface antigen, anti-HCV hepatitis C virus antibody, AFP α-fetoprotein, TBIL total bilirubin, ALB albumin, PT pro-thrombin time, ALT alanine aminotransferase, PLT platelet count, WBC white blood cell, CSPH clinical significant portal hypertension, PVTT portal vein tumor thrombus