Fig. 1
From: Transmembrane protein 108 involves in adult neurogenesis in the hippocampal dentate gyrus
High Tmem108 expression area in mice brain. A Tmem108 relative expression in different tissues in adult wild type mice (Gapdh expression as internal control, Tmem108 expression in heart was defined as one, wild type mice n = 3). B Tmem108 mutant mice targeting strategy; the initiation code of Tmem108 localizes in the exon 3, and LacZ gene is inserted into the downstream of Tmem108 promotor. C LacZ staining of Tmem108 mutant mouse (Tmem108 +/−) hippocampus; PMCo: posteromedial cortical amygdaloid nucleus, PTN: Parafascicular thalamic nucleus. D Tmem108 levels in hippocampus were evaluated by Western blotting assay; D (a) Representative image of Western blotting assays, D (b) Statistics of Tmem108 expression from Western blotting assay; 1: wild type mice n = 3; 2: Tmem108 knockout mice homozygous (Tmem108 −/−) n = 3; 3: Tmem108 knockout mice heterozygous (Tmem108 +/−) n = 3