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TableĀ 1 Cell-type specific effect of TRAF3 deficiency on type I IFN induction

From: Cell type-specific function of TRAF2 and TRAF3 in regulating type I IFN induction

Pathways Inducers Cell types
MEFs BMDM BMDC
RIG-I pathway VSV Inhibited No effect No effect
Sev Inhibited No effect No effect
Lipo/PolyI:C Inhibited NA No effect
STING pathway HSV1 Upregulated Upregulated No effect
Lipo/cGAMP Inhibited NA No effect
Lipo/ISD Inhibited NA NA
DMXAA Inhibited NA NA
TRIF pathway LPS NA No effect Inhibited
PolyI:C NA No effect Inhibited
  1. NA not analyzed