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Table 2 Sensitivity, specificity, and positive and negative predictive values for evaluating GISTs risk category using TIPE2 IHC expression

From: TIPE2 acts as a biomarker for GIST risk category and suppresses the viability and invasiveness of GIST cells

IHC scores Sensitivity 95% CI Specificity 95% CI PPV 95% CI NPV 95% CI Significance
≤ 2 74.67 63.3–84.0 71.43 47.8–88.7 90.3 80.1–96.4 44.1 27.2–62.1 High risk prediction
  1. PPV positive predictive value, NPV negative predictive value