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Fig. 5 | Cell & Bioscience

Fig. 5

From: TUG1 confers cisplatin resistance in esophageal squamous cell carcinoma by epigenetically suppressing PDCD4 expression via EZH2

Fig. 5

PDCD4 knockdown reversed the enhancive effect of down-regulated TUG1 on DDP sensitivity of ESCC cells. ECA109/DDP and EC9706/DDP cells were transfected with si-con, si-TUG1 or si-TUG1 + PDCD4, followed by determination of PDCD4 expression by qRT-PCR analysis (a, b), IC50 of DDP by MTT assay (c, d), and cell apoptosis by flow cytometry analysis (e, f). *P < 0.05

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