Fig. 4

PDCD4 overexpression improved DDP sensitivity of ESCC cells. ECA109/DDP and EC9706/DDP cells were transfected with Vector or PDCD4, followed by determination of PDCD4 expression by qRT-PCR and western blot analyses (a, b), IC50 of DDP by MTT assay (c, d), and cell apoptosis by flow cytometry analysis (e, f). *P < 0.05