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Fig. 3 | Cell & Bioscience

Fig. 3

From: Circ_0027599/PHDLA1 suppresses gastric cancer progression by sponging miR-101-3p.1

Fig. 3

Circ_0027599 acted as a sponge of miR-101 and up-regulates PHLDA1 expression in gastric cancer. a The information of circ_0027599 from circRNA database. b The luciferase activity decreased in MKN-28 cells transfected with miR-101. The luciferase activity was assayed by dual luciferase reporter system. c miR-101 levels were up-regulated in MKN-28 and HGC-27 cells transfected with circ_0027599 siRNA. MiR-101 levels were analyzed by qRT-PCR. d Circ_0027599 expression was down-regulated in MKN-28 and HGC-27 cells transfected with miR-101 mimics. Circ_0027599 levels were analyzed by qRT-PCR. e Circ_0027599 expression was up-regulated in MKN-28 and HGC-27 cells were transfected with miR-101 inhibitors. Circ_0027599 levels were analyzed by qRT-PCR. **p < 0.01

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