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Fig. 5 | Cell & Bioscience

Fig. 5

From: TIPE2 acts as a biomarker for tumor aggressiveness and suppresses cell invasiveness in papillary thyroid cancer (PTC)

Fig. 5

TIPE2 suppressed uPA and MMP9 expression via inhibiting Rac1 in PTC cells. a The expression of uPA and MMP9 at mRNA level were detected by real-time PCR after transfection with Mock, wild type TIPE2 and mutant TIPE2 plasmids in PTC cells. b The protein level of uPA and MMP9 were detected by ELISA in PTC cells after transfected with Mock, wild type TIPE2 and mutant TIPE2 plasmids. c The expression of uPA and MMP9 at mRNA level were detected by real-time PCR in TPC-1 and B-CPAP cells after Rac1 silencing. d The protein level of uPA and MMP9 were detected by ELISA in TPC-1 and B-CPAP cells after Rac1 silencing

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