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Fig. 6 | Cell & Bioscience

Fig. 6

From: All-trans retinoic-acid inhibits heterodimeric bone morphogenetic protein 2/7-stimulated osteoclastogenesis, and resorption activity

Fig. 6

BMP2/7 (5 or 50 ng/ml) ± ATRA (1 µM) modulated osteoclast resorption activity. Representative microscopic image of calcium phosphate resorption by osteoclasts in different groups: a control, b 5 ng/ml BMP2/7, c 50 ng/ml BMP2/7, and d 50 ng/ml BMP2/7 + ATRA. e Semi-quantitative analysis of area of resorption pits. X indicates nil. All data are presented as mean ± SD, from three independent experiments. Significant effect of the treatment, ****p < 0.0001

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