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Fig. 3 | Cell & Bioscience

Fig. 3

From: All-trans retinoic-acid inhibits heterodimeric bone morphogenetic protein 2/7-stimulated osteoclastogenesis, and resorption activity

Fig. 3

BMP2/7 (5 or 50 ng/ml) ± ATRA (1 µM) modulated osteoclast marker and RARs gene expression in BMM cell cultures (ac). df RARs, g C-fos and h DC-Stamp expression in RAW264.7 cells. Values are mean ± SD, from three independent experiments. Significant effect of the treatment **p < 0.01, ***p < 0.001, ****p < 0.0001

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