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Fig. 6 | Cell & Bioscience

Fig. 6

From: Proteomic characterization of endogenous substrates of mammalian ubiquitin ligase Hrd1

Fig. 6

Hrd1 regulates the stability of both OS9.1 and OS9.2. ac Cycloheximide chase analysis of OS9 degradation in control or Hrd1 null CRISPR cells. Note that the lysate samples from Hrd1 CRISPR cells were loaded at 20% of the control samples. The graphs in b, c show quantification of 4 independent experiments. Error bars, sem, n = 4. **p-value < 0.01, ***p-value < 0.005. d Synovia isolated from rheumatoid arthritis (RA) or osteoarthritis (OA) were analyzed by immunoblotting

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