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Fig. 4 | Cell & Bioscience

Fig. 4

From: Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington’s disease

Fig. 4

IRP1 mRNA level is increased in both N171-82Q mice brain and 160Q HEK293 cells. a1c1 IRP1 mRNA level was detected by RT-PCR both in the brain of TG mice (a1 cortex; b1 striatum) and in 160Q HEK293 cells (c1). a2c2 Quantitative representation of IRP1 band intensity normalized to β-actin. IRP1 mRNA level is increased both in TG mice brain and in 160Q HEK293 cells compared to controls. n = 4. *p < 0.05 compared to WT mice, or 20Q HEK293 cells

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