Fig. 3
From: Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington’s disease
IRP1 protein level is increased in both N171-82Q mice brain and 160Q HEK293 cells. a1–c1 IRP1 protein expression was detected by Western blotting both in the brain of TG mice (a1 cortex; b1 striatum) and in 160Q HEK293 cells (c1). a2–c2 Quantitative representation of IRP1 band intensity normalized to GAPDH. IRP1 protein level is increased both in TG mice brain and in 160Q HEK293 cells compared to controls. n = 4. *, p < 0.05 compared to WT mice, or 20Q HEK293 cells