Fig. 1
From: INAVA promotes aggressiveness of papillary thyroid cancer by upregulating MMP9 expression
INAVA is upregulated in PTC and is associated with LN metastasis. a The expression of INAVA in 59 pairs of primary PTC (T) versus their paired non-cancerous thyroid tissues (N) using RNAseq data sets deposited on TCGA. b The expression of INAVA in 16 paired T and N was assessed by real time RT-PCR. GAPDH was used as a house keeping gene control. c Representative images of IHC assays on INAVA expression in PTC specimens from the studied cohort. NLN with no lymph node metastasis, LN with lymph node metastasis. d Percentage of specimens showing low (n = 57) or high (n = 55) INAVA expression in relation to the LN metastasis. *P < 0.05