Fig. 7

Effect of RSV on activating Wnt/β-catenin signaling in osteogenic differentiation in vivo. a ALP activity in calvaria of mouse PIO model pretreated with RSV (10 mg/kg/day) with or without ICG-001 (10 μL). b The mRNA expression levels of β-catenin in calvaria of mouse PIO model pretreated with RSV (10 mg/kg/day) with or without ICG-001 (10 μL). c The mRNA and protein expression levels of Runx2, Osterix and OCN in calvaria of mouse PIO model pretreated with RSV (10 mg/kg/day) with or without ICG-001 (10 μL). *P < 0.05 compared with sham group. ^&P < 0.05 compared with vehicle group. ^#P < 0.05 compared with RSV group