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Fig. 6 | Cell & Bioscience

Fig. 6

From: Hypoxia-induced the upregulation of stromal cell-derived factor 1 in fibroblast-like synoviocytes contributes to migration of monocytes into synovium tissue in rheumatoid arthritis

Fig. 6

Hypoxia-treated fibroblast-like synoviocytes induced monocytes differentiated into macrophages and secreted inflammatory factors. a Expression of macrophages markers were measured by RT-PCR with the treatment of hypoxia-disposed FLSs’ culture medium. b and c Inflammatory factors (IL-6, TNF-α, IL-1β and MMP-3) levels were detected by RT PCR and ELISA in monocytes with the treatment of hypoxia-disposed FLSs’ culture medium. **P < 0.01, ***P < 0.001

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