Fig. 4

Hypoxia induced SDF-1 expression through activation of NF-κB signaling pathway in fibroblast-like synoviocytes. a Phosphorylate-IκB expression was detected by western blot in hypoxia-treated fibroblast-like synoviocytes. b Phosphorylate-IκB and SDF-1 expression was measured by western blot in hypoxia-treated fibroblast-like synoviocytes with dispose of NF-κB inhibitor, BAY 11-7082. c RT-PCR was performed to examine SDF-1 level in in hypoxia-treated fibroblast-like synoviocytes with dispose of NF-κB inhibitor, BAY 11-7082. d ELISA was performed to examine SDF-1 level in in hypoxia-treated fibroblast-like synoviocytes with dispose of NF-κB inhibitor, BAY 11-7082