Fig. 5

a The MAPT expression level was determined by qRT-PCR and western blot assays in MDA-MB-231 and MDA-MB-468 cells transfected with siRNA-1/2 or negative control. b The MAPT expression level was determined by qRT-PCR and western blot assays in the two cell lines transfected with MAPT-AS1 vector or empty vector. c The MAPT-AS1 expression level was measured by qRT-PCR in MDA-MB-231 and MDA-MB-468 cells transfected with si-MAPT or negative control. d The MAPT expression level was detected by qRT-PCR and western blot assays in the two cell lines after treated with different concentrations of paclitaxel for 24 h, while the MAPT-AS1 expression level was measured by qRT-PCR. e The MDA-MB-231 and MDA-MB-468 cells were pretreated with si-MAPT, then transfected with MAPT-AS1 vector or empty vector. The MAPT expression level was determined by qRT-PCR and western blot assays. f The MAPT and MAPT-AS1 expression levels in breast tumor tissues from TCGA database