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Fig. 2 | Cell & Bioscience

Fig. 2

From: Knockdown of LncRNA MAPT-AS1 inhibites proliferation and migration and sensitizes cancer cells to paclitaxel by regulating MAPT expression in ER-negative breast cancers

Fig. 2

a The MAPT-AS1 expression level was determined by qRT-PCR in MDA-MB-231 and MDA-MB-468 cells transfected with siRNAs. GAPDH was used as control. b, c The MDA-MB-231 and MDA-MB-468 cells were transfected with siRNA-1/2 or negative control for 48 h. The relative cell proliferation was measured using CCK-8 assays and colony-forming assays. d, e The migration and invasion ability of the two cell lines transfected with siRNA-1/2 or NC were measured by Transwell assays. f, g The two cell lines transfected with siRNA-1/2 or NC were then treated with paclitaxel for 24 h before CCK-8 assays or apoptosis detection. The apoptosis rate were measured using flow cytometry assays

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