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Fig. 1 | Cell & Bioscience

Fig. 1

From: Knockdown of LncRNA MAPT-AS1 inhibites proliferation and migration and sensitizes cancer cells to paclitaxel by regulating MAPT expression in ER-negative breast cancers

Fig. 1

a Coding potential calculator 2 (CPC 2.0) was used to predict GAPDH, HOTAIR and MAPT-AS1′ protein-coding probability. b MAPT-AS1 is an 840 bp RNA transcribed from chromosome 17, the opposite strand of MAPT (17q21.31). c MAPT-AS1 levels in the nucleus and cytoplasmic compartments of MDA-MB-231 and MDA-MB-468 cells were detected using qRT-PCR. GAPDH was used as the cytoplasmic control, and U6 snoRNA was used as the nuclear control. d MAPT-AS1 expression level was determined in the ER-negative breast cell lines with qRT-PCR. eh ER-negative patients with younger age (< 60), larger tumors (≥ 2 cm), metastatic lymph nodes and stages (III–IV) had higher expression of MAPT-AS1

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