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Fig. 7 | Cell & Bioscience

Fig. 7

From: Long non-coding RNA CASC2 improved acute lung injury by regulating miR-144-3p/AQP1 axis to reduce lung epithelial cell apoptosis

Fig. 7

LPS induced A549 cell apoptosis by regulating CASC2/miR-144-3p/AQP1 axis. The A549 cell was transfected or co-transfected of pcDNA-CASC2, miR-144-3p mimic and pcDNA-AQP1 and induced by LPS. And then the cell apoptosis was detected by MTT, and demonstrated by caspase-3 expression. a The inhibited cell apoptosis by pcDNA-CASC2 was reversed by miR-144-3p mimic, while which was reversed again by pcDNA-AQP1. b The caspase-3 expression by western blot. c A549 cell apoptosis in different groups using flow cytometry assay. *P < 0.05 vs pcDNA, #P < 0.05 vs pre-NC, &P < 0.05 vs miR-144-3p mimic

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